Opioid dependence and substitution therapy: thymoquinone as potential novel supplement therapy for better outcome for methadone maintenance therapy substitution therapy

opioid dependence and substitution therapy: thymoquinone as potential novel supplement therapy for better outcome for methadone maintenance therapy substitution therapy

methadone is widely being used for opioid substitution therapy. however, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. this article is written to higlights th...

Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence.

BACKGROUND Methadone maintenance was the first widely used form of opioid replacement therapy developed to treat heroin dependence, and it remains the best-researched treatment for this problem. Despite the widespread use of methadone in maintenance treatment for opioid dependence in many countries, it is a controversial treatment whose effectiveness has been disputed. OBJECTIVES To evaluate ...

How to improve Opioid Substitution Therapy implementation

Opioid substitution therapy in resource-poor settings.

Approximately 10% of new HIV infections worldwide are attributable to injecting drug use, often of an opiate such as heroin. 1 Opioid substitution therapy supplies illicit drug users with a replacement drug, a prescribed medicine such as methadone or buprenorphine, which is usually administered orally in a supervised clinical setting. The effectiveness of this therapy is recognized in developed...

assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.

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